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Listar por autor "Silva, Sonia"
Mostrando ítems 1-5 de 5
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Artículo
BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair
Sessa, Gaetana; Gómez González, Belén María; Silva, Sonia; Pérez Calero, Carmen; Beaurepere, Romane; Barroso Ceballos, Sonia Inés; Martineau, Sylvain; Martin, Charlotte A.; Ehlén, Åsa; Martínez, Juan S.; Lombard, Bérangére; Loew, Damarys; Vagner, Stéphan; Aguilera López, Andrés; Carreira, Aura (Wiley-Blackwell, 2021)The BRCA2 tumor suppressor is a DNA double-strand break (DSB) repair factor essential for maintaining genome integrity. ...
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Artículo
Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
Silva, Sonia; Pérez de Camino Cantos, Dolores; Aguilera López, Andrés (2018)R loops are nucleic acid structures comprising an DNA-RNA hybrid and a displaced single-stranded DNA. These structures may ...
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Artículo
Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
Silva, Sonia; Altmannova, Veronika; Luke Glaser, Sarah; Henriksen, Peter; Gallina, Irene; Yang, Xuejiao; Choudhary, Chunaram; Luke, Brian; Krejci, Lumir; Lisby, Michael (Cold Spring Harbor Laboratory Press, 2016)Mph1 is a member of the conserved FANCM family of DNA motor proteins that play key roles in genome maintenance processes ...
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Artículo
SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination
Silva, Sonia; Lisby, Michael (Elsevier, 2016)Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, ...
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Artículo
The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage
Lafuente Barquero, Juan; Luke Glaser, Sarah; Graf, Marco; Silva, Sonia; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2017)RNA-DNA hybrids are naturally occurring obstacles that must be overcome by the DNA replication machinery. In the absence ...